5 Results for "

murine chondrocytes

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "murine chondrocytes" in MCE Product Catalog:

  • Targets Recommended:
1
BMP-4 (15-24) acetate
BMP-4 (15-24) acetate
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1 Cited Publications
Cat. No.: HY-P10710A
Target:  

IFNAR Interleukin Related COX NO Synthase

Research Areas:  

Inflammation/Immunology

BMP-4 (15-24) acetate is a cell-penetrating heparin-binding peptide with the sequence RKKNPNCRRH. BMP-4 (15-24) acetate exhibits anti-inflammatory and anti-chondrogenic activities. BMP-4 (15-24) acetate can be used in the research of arthritis .
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WYRGRL
WYRGRL
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Cat. No.: HY-P10739
CAS No.: 1021155-39-4
Target:  

Exosomes Collagen

Research Areas:  

Inflammation/Immunology

WYRGRL is a selective, high-affinity collagen type II-binding peptide with a IC50 of 140 nM. Collagen type II is the most abundant and specific structural protein in the extracellular matrix of articular cartilage. WYRGRL can precisely target small-molecule compounds such as Dexamethasone (HY-14648) and nanocarrier-engineered exosomes to cartilage, significantly enhancing their therapeutic effects on osteoarthritis .
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BMP-4 (15-24)
BMP-4 (15-24)
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Cat. No.: HY-P10710
CAS No.: 1629625-47-3
Target:  

IFNAR Interleukin Related COX NO Synthase

Research Areas:  

Inflammation/Immunology

BMP-4 (15-24) is a cell-penetrating heparin-binding peptide with the sequence RKKNPNCRRH. BMP-4 (15-24) exhibits anti-inflammatory and anti-chondrogenic activities. BMP-4 (15-24) can be used in the research of arthritis .
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PDRN
PDRN
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Cat. No.: HY-W250160
CAS No.: 100403-24-5
Synonyms: Polydeoxyribonucleotide
Category:  

Natural Products Animals

Target:  

Adenosine Receptor Autophagy PKA VEGFR ERK Akt Microphthalmia Associated Transcription Factor (MITF) Tyrosinase Sirtuin Apoptosis DNA/RNA Synthesis

PDRN (Polydeoxyribonucleotide) is a deoxynucleotide polymer mainly derived from the sperm of rainbow trout or salmon. PDRN inhibits pro-inflammatory factors and promotes VEGF expression via the cAMP-PKA pathway by activating the adenosine A2A receptor (A2AR), thereby driving angiogenesis and collagen deposition in fibroblasts. Degradation products of PDRN provide DNA raw materials for proliferating cells through the salvage synthesis pathway, accelerating re-epithelialization. PDRN reduces melanin synthesis and cell apoptosis by upregulating ERK/AKT phosphorylation and inhibiting the activities of MITF and tyrosinase, and resists skin aging by attenuating nuclear autophagy and blocking the interaction between LC3-SIRT1. PDRN is mainly used for wound repair, post-aesthetic surgery recovery and anti-aging research .
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WYRGRLC
WYRGRLC
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Cat. No.: HY-P10739C
CAS No.: 1027630-05-2
Target:  

Collagen Apoptosis

Research Areas:  

Inflammation/Immunology

WYRGRLC is a type II collagen-targeting peptide. WYRGRLC specifically binds to type II collagen α1 in articular cartilage in a sequence-dependent manner. WYRGRLC inhibits the binding of WYRGRL-displaying phage (C1-3) to articular cartilage in a sequence-specific manner. WYRGRLC can act as a retention enhancer to improve the cartilage-targeting ability of polymeric nanoparticles and liposomal nanoplatforms, facilitating the delivery of Rapamycin (HY-10219) to chondrocytes. WYRGRLC can be used in studies related to osteoarthritis .
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