6 Results for "

neuroregeneration

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "neuroregeneration" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-111793
CAS No.: 1060524-97-1
Purity:  98.40%
Target:  

CXCR

Research Areas:  

Neurological Disease

NUCC-390 is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 induces internalization of CXCR4 receptors and acts in an opposite way of AMD3100 (HY-10046) . NUCC-390 promotes nerve recovery of function after neurodegeneration in vivo .
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6
6 Cited Publications
Cat. No.: HY-111793A
CAS No.: 2749281-71-6
Purity:  98.19%
Target:  

CXCR

Research Areas:  

Neurological Disease

NUCC-390 dihydrochloride is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 dihydrochloride induces internalization of CXCR4 receptors and acts in an opposite way of AMD3100 (HY-10046) . NUCC-390 dihydrochloride promotes nerve recovery of function after neurodegeneration in vivo .
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Cat. No.: HY-P99359
CAS No.: 1791416-49-3
Synonyms: ABT-555; AE12-1Y-QL; Anti-RGMA Reference Antibody (elezanumab)

Target:  

TGF-beta/Smad

Research Areas:  

Metabolic Disease

Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism .
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Cat. No.: HY-P99959
CAS No.: 2379805-59-9
Synonyms: MT-3921; rH116A3

Target:  

TGF-β Receptor

Research Areas:  

Neurological Disease

Unasnemab (MT-3921) is a humanised IgG1 monoclonal antibody that binds to repulsive guidance molecule A (RGMa). Unasnemab improves locomotor function and promotes neuroregeneration. Unasnemab exerts ameliorative effects on hippocampal neurogenesis impairment and cognitive decline in db/db mice, Streptozotocin (STZ) (HY-13753)-induced type 1 diabetic and bilateral common carotid artery stenosis (BCAS)-induced mice. Unasnemab can be used for the research of spinal cord injury, diabetes-induced neurological impairments .
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Cat. No.: HY-121850
CAS No.: 2829-19-8
Synonyms: EX-4883
Target:  

HBV

Research Areas:  

Neurological Disease

Rolicyprine (EX-4883) is an antidepressant with neuroprotective activity. Rolicyprine can improve depressive symptoms and promote neuroregeneration. Rolicyprine also shows potential effectiveness for anxiety suppression .
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Cat. No.: HY-111793AR
CAS No.: 2749281-71-6
Research Areas:  

Neurological Disease

NUCC-390 dihydrochloride (Standard) is the analytical standard of NUCC-390 (dihydrochloride) (HY-111793A). This product is intended for research and analytical applications. NUCC-390 dihydrochloride is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 dihydrochloride induces internalization of CXCR4 receptors and acts in an opposite way of AMD3100 (HY-10046) . NUCC-390 dihydrochloride promotes nerve recovery of function after neurodegeneration in vivo .
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