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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
neutrophil PDE4
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "neutrophil PDE4" in MCE Product Catalog:
Cat. No.: HY-W700638A
CAS No.: 76166-55-7
Synonyms: AH 21-132
Target:
Research Areas:
Benafentrine maleate is a phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) inhibitor with bronchodilator activity. Benafentrine maleate has IC50 values of 1.74 μM and 1.76 μM for guinea pig platelet PDE3 and neutrophil PDE4, respectively. Benafentrine maleate can be used in research related to obstructive airway diseases .
Cat. No.: HY-117954
CAS No.: 216884-02-5
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Research Areas:
CC-3052 is a phosphodiesterase 4 (PDE4) inhibitor with immunomodulatory activities. CC-3052 reduces neutrophil apoptosis in HIV⁺. CC-3052 is promising for research of HIV-related diseases .
Cat. No.: HY-W700638
CAS No.: 35135-01-4
Target:
Research Areas:
Benafentrine is a phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) inhibitor with bronchodilator activity. Benafentrine has IC50 values of 1.74 μM and 1.76 μM for guinea pig platelet PDE3 and neutrophil PDE4, respectively. Benafentrine can be used in research related to obstructive airway diseases .
Cat. No.: HY-114052
CAS No.: 426268-06-6
Target:
Research Areas:
NVP-ABE171 is an efficient, long-lasting and orally active PDE4 inhibitor with IC50 values for PDE4D, PDE4B, PDE4A and PDE4C of 1.5, 34, 602 and 1230 nM respectively. NVP-ABE171 enhances the cAMP accumulation induced by isoproterenol, inhibits the oxidative burst of eosinophils and the release of inflammatory cytokines from T cells and monocytes. NVP-ABE171 exhibits potent anti-inflammatory activity in animal models of asthma and pulmonary inflammation. NVP-ABE171 can be used for research on asthma and chronic obstructive pulmonary disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
