Benafentrine maleate
Benafentrine maleate is a phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) inhibitor with bronchodilator activity. Benafentrine maleate has IC50 values of 1.74 μM and 1.76 μM for guinea pig platelet PDE3 and neutrophil PDE4, respectively. Benafentrine maleate can be used in research related to obstructive airway diseases.
For research use only. We do not sell to patients.
- CAS No.: 76166-55-7
- Formula: C31H35N3O11
- Molecular Weight:625.62
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
PDE3 1.74 μM (IC50) |
PDE4 1.76 μM (IC50) |
In Vitro
Chemical Information
-
CAS No. 76166-55-7
-
Molecular Weight 625.62
-
Formula C31H35N3O11
-
SMILES
OC(/C=C\C(O)=O)=O.COC1=C(OC)C=C([C@@]2([H])[C@@](CCN(C2)C)([H])N=C3C4=CC=C(C=C4)NC(C)=O)C3=C1.OC(/C=C\C(O)=O)=O
-
Synonyms
AH 21-132
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Benafentrine maleate Related Classifications
HY-W700638A Related Classifications
Powered by Bioz
Keywords
- Benafentrine
- 76166-55-7
- AH 21-132
- Phosphodiesterase (PDE)
- guinea-pig platelet PDE3
- guinea pig peritoneal macrophages
- neutrophil PDE4
- cAMP hydrolysis
- guinea-pig macrophage lysates
- phosphodiesterase 4
- CPPDE4
- isoprenaline-induced cAMP accumulation
- obstructive airways disease
- phosphodiesterase 3
- Inhibitor
- inhibitor
- inhibit