35135-01-4
Chemical Structure
Benafentrine
- CAS 番号: 35135-01-4
- Formula:C23H27N3O3
- Molecular Weight:393.49
IUPAC Name: N-(4-((4aS,10bR)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin-6-yl)phenyl)acetamide
InChIKey: DCDXHGMCXGHXBM-PMACEKPBSA-N
SMILES: O(C)C=1C=C2C([C@]3([C@@](N=C2C4=CC=C(NC(C)=O)C=C4)(CCN(C)C3)[H])[H])=CC1OC
Biological Activity: Benafentrine is a phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) inhibitor with bronchodilator activity. Benafentrine has IC50 values of 1.74 μM and 1.76 μM for guinea pig platelet PDE3 and neutrophil PDE4, respectively. Benafentrine can be used in research related to obstructive airway diseases[1].
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Benafentrine | Benafentrine is a phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) inhibitor with bronchodilator activity. Benafentrine has IC50 values of 1.74 μM and 1.76 μM for guinea pig platelet PDE3 and neutrophil PDE4, respectively. Benafentrine can be used in research related to obstructive airway diseases. | |||||||||||||||||||||
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