1 Result for "

nor-Binaltorphimine dihydrochloride (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "nor-Binaltorphimine dihydrochloride (Standard)" in MCE Product Catalog:

Cat. No.: HY-100903R
CAS No.: 113158-34-2
Synonyms: nor-Binaltorphimine dihydrochloride (Standard); nor-BNI dihydrochloride (Standard)
Research Areas:  

Neurological Disease

Norbinaltorphimine dihydrochloride (Standard) is the analytical standard of Norbinaltorphimine dihydrochloride (HY-100903). This product is intended for research and analytical applications. Norbinaltorphimine dihydrochloride (nor-Binaltorphimine dihydrochloride; nor-BNI dihydrochloride) is a selective, long-acting competitive antagonist of the κ-opioid receptor. Norbinaltorphimine dihydrochloride blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. Norbinaltorphimine dihydrochloride suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. Norbinaltorphimine dihydrochloride is applicable to research related to neurological disorders such as pain .
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