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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
secreted phospholipases A2
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "secreted phospholipases A2" in MCE Product Catalog:
Cat. No.: HY-122756
CAS No.: 14379-42-1
Synonyms: GK144
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N-Palmitoyl-l-leucine (GK144) is a secreted phospholipases A2 inhibitor. N-Palmitoyl-l-leucine can be used for inflammatory diseases .
Synonyms: GK115
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CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases .
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
GSK2647544 is an orally available, selective inhibitor of Lp-PLA2. Lipoprotein-associated phospholipase (Lp-PLA2) is a calcium-independent phospholipase A2 with proinflammatory activities that is primarily secreted by monocyte-derived macrophages .
Cat. No.: HY-125157
CAS No.: 172732-62-6
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Me-Indoxam is a potent and cell-impermeable secreted phospholipase A2 (sPLA2) inhibitor .
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ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s) with an IC50 of 80 nM, specially targeting hGX. ROC-0929 inhibits the phosphorylation of ERK1/2 and p-38. Secreted phospholipases A2 (sPLA2s) are a family of disulfide-rich, Ca 2+-dependent enzymes that hydrolyze the sn-2 position of glycero-phospholipids to release a fatty acid and a lysophospholipid. ROC-0929 has the potential for researching inflammation related diseases .
Cat. No.: HY-112605
CAS No.: 2241025-50-1
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sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively .
Cat. No.: HY-134082A
CAS No.: 84601-19-4
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(Z)-Oleyloxyethyl phosphorylcholine ((Z)-OPC) is an isomer of Oleyloxyethyl phosphorylcholine (OPC). Oleyloxyethyl phosphorylcholine is an inhibitor of secreted Phospholipase A2 (sPLA2), which is involved in the biosynthesis of proinflammatory lipid media. Oleyloxyethyl phosphorylcholine can be used to study inflammatory diseases. Oleyloxyethyl phosphorylcholine also modified the red blood membrane and was used to bind the oxygen-carrying liquid perfluorocarbons as an antivenom agent to reduce toxin-induced hemolysis .
Cat. No.: HY-E70616
Secreted Phospholipase A2-IIA, Human (EC 3.1.1.4), belongs to the family of antimicrobial peptides, hydrolyzes phospholipids to liberate lysophospholipids and fatty acids. Secreted Phospholipase A2-IIA, Human (EC 3.1.1.4) efficiently hydrolyzes bacterial membranes .
Cat. No.: HY-N21818
CAS No.: 172854-76-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
