1 Result for "

tetrahydrofolate derivatives

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "tetrahydrofolate derivatives" in MCE Product Catalog:

Cat. No.: HY-187636
CAS No.: 18921-70-5
Research Areas:  

Cancer

Methasquin is an antifolate dihydrofolate reductase inhibitor (antifolate dihydrofolate reductase) with an IC50 of 1.3 nM against dihydrofolate reductase derived from human leukemia cells. Methasquin binds to dihydrofolate reductase, depletes tetrahydrofolate derivatives, disrupts thymidylate synthesis and inhibits DNA synthesis. Methasquin can be used in leukemia-related research .
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