11 Results for "

tonic-clonic seizures

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "tonic-clonic seizures" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-B0495
CAS No.: 84057-84-1
Synonyms: LTG; BW430C
Research Areas:  

Neurological Disease Cancer

Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al .
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Cat. No.: HY-B1112
CAS No.: 333-36-8
Synonyms: Bis(2,2,2-trifluoroethyl) ether; Flurothyl
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Fluorothyl (Bis (2,2,2-trifluoroethyl) ether; Flurothyl) is a GABAA receptor modulator and epileptogenic agent. Fluorothyl induces generalized epilepsy in mice. Fluorothyl is used for epilepsy research .
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Cat. No.: HY-W017500
CAS No.: 17833-53-3
N-Methyl-DL-aspartic acid acts as an agonist for N-methyl-D-aspartic acid receptors and D-isomer-specific aspartate receptors. N-Methyl-DL-aspartic acid activates hypothalamic neurons that regulate gonadotropin-releasing hormone secretion, and stimulates prepubertal male rhesus monkeys to produce sustained intermittent gonadotropin-releasing hormone secretion and pulsatile luteinizing hormone secretion. N-Methyl-DL-aspartic acid activates excitatory effects mediated by N-methyl-D-aspartic acid receptors. N-Methyl-DL-aspartic acid exhibits convulsant effects, inducing clonic convulsions with loss of righting reflex, generalized tonic-clonic seizures or persistent clonic seizures. N-Methyl-DL-aspartic acid causes precocious puberty. N-Methyl-DL-aspartic acid can be used in studies related to convulsions and seizures .
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Cat. No.: HY-P2707
CAS No.: 74504-53-3
Synonyms: α-DTX
Research Areas:  

Neurological Disease

α-Dendrotoxin (α-DTX) is a voltage-gated K + channel blocker and an acid-sensing ion channel (ASIC) inhibitor. α-Dendrotoxin blocks Kv1.1, Kv1.2, Kv1.6 and D-type (ID) voltage-gated K + channels, and reversibly inhibits slowly inactivating potassium currents. α-Dendrotoxin induces epilepsy-related behaviors in mice. α-Dendrotoxin can be used in studies related to tonic-clonic seizures .
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Cat. No.: HY-123681
CAS No.: 98164-11-5
Target:  

Others

Research Areas:  

Neurological Disease

R 57720 is an antiepileptic agent that exhibits dose-dependent anticonvulsant activity across multiple postnatal rat age groups. R 57720 inhibits severe generalized tonic-clonic seizures induced by Pentylenetetrazol. R 57720 can be used for epilepsy research .
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Cat. No.: HY-101708
CAS No.: 97627-24-2
Purity:  99.73%
Research Areas:  

Neurological Disease

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent with potential for the treatment of generalized tonic-clonic and partial seizures.
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Cat. No.: HY-10420
CAS No.: 89592-45-0
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

ZK-93426 is a benzodiazepine receptor antagonist. ZK-93426 does not alter the dogs' motility but induces generalized myoclonic jerks and tonic-clonic seizures. ZK-93426 can be used to study the mechanism of withdrawal reactions in the state of benzodiazepine dependence .
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Cat. No.: HY-171182
CAS No.: 130403-18-8
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

D3017 is the main metabolite of D2624, which has oral bioactivity and anti-convulsant effects. D3017 ED50 value is 1.5 mg/kg in mice, and it can be used for research on severe generalized tonic-clonic seizures (grand mal) and complex partial epilepsy .
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Cat. No.: HY-B0495A
CAS No.: 375347-20-9
Synonyms: LTG hydrate; BW430C hydrate
Research Areas:  

Neurological Disease Cancer

Lamotrigine hydrate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine hydrate selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine hydrate can be used for the research of epilepsy, focal seizure, et al .
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Cat. No.: HY-B0495S6
Synonyms: LTG-13C2,15N2,d3; BW430C-13C2,15N2,d3
Lamotrigine- 13C2, 15N2,d3 is 15N and deuterated labeled Lamotrigine (HY-B0495). Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al .
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Cat. No.: HY-119716
CAS No.: 7199-29-3
Research Areas:  

Neurological Disease

Cyheptamide is an orally active anticonvulsant and antiepileptic agent. Cyheptamide exhibits moderate acute toxicity in animal models, with lethal doses varying by species specificity. Cyheptamide can be used in studies related to convulsions and epilepsy .
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