2. Membrane Transporter/Ion Channel
  3. Synaptic Vesicle Proteins
  4. Seletracetam

Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy.

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Seletracetam

Seletracetam Estructura química

No. CAS : 357336-74-4

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
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200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of Seletracetam:

Seletracetam Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Seletracetam

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy[1][2][3].

IC50 & Target

SV2A[1]
In Vitro

Seletracetam decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A[2].
Seletracetam decreases synaptic responses in a time-, frequency- and concentration-dependent manner[2].
Seletracetam modifies rates of presynaptic release[2].
Seletracetam inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Seletracetam Related Antibodies
Ensayo clínico
Peso molecular

232.23

Fòrmula

C10H14F2N2O2
No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C([C@@H](N1C(C[C@H](C1)/C=C(F)\F)=O)CC)N
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvente y solubilidad
In Vitro: 

DMSO : 200 mg/mL (861.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3061 mL 21.5304 mL 43.0608 mL
5 mM 0.8612 mL 4.3061 mL 8.6122 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.70%

SDS (252 KB)

COA (252 KB) HNMR (205 KB) LCMS (87 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.3061 mL 21.5304 mL 43.0608 mL 107.6519 mL
5 mM 0.8612 mL 4.3061 mL 8.6122 mL 21.5304 mL
10 mM 0.4306 mL 2.1530 mL 4.3061 mL 10.7652 mL
15 mM 0.2871 mL 1.4354 mL 2.8707 mL 7.1768 mL
20 mM 0.2153 mL 1.0765 mL 2.1530 mL 5.3826 mL
25 mM 0.1722 mL 0.8612 mL 1.7224 mL 4.3061 mL
30 mM 0.1435 mL 0.7177 mL 1.4354 mL 3.5884 mL
40 mM 0.1077 mL 0.5383 mL 1.0765 mL 2.6913 mL
50 mM 0.0861 mL 0.4306 mL 0.8612 mL 2.1530 mL
60 mM 0.0718 mL 0.3588 mL 0.7177 mL 1.7942 mL
80 mM 0.0538 mL 0.2691 mL 0.5383 mL 1.3456 mL
100 mM 0.0431 mL 0.2153 mL 0.4306 mL 1.0765 mL
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Seletracetam Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Seletracetam357336-74-4Ucb 44212Ucb44212Ucb-44212Synaptic Vesicle ProteinsSVSV2AantiepilepticepilepsyInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Seletracetam
Cat. No.:
HY-119810
Cantidad:
MCE Japan Authorized Agent:

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