Survivin-IN-1
Survivin-IN-1 (Compound II₃) is a potent Survivin (a member of the Inhibitor of Apoptosis Protein family) inhibitor with an IC50 value of 8.1 μM against human lung cancer A549 cells and 9.0 μM against breast cancer MCF-7 cells. Survivin-IN-1 reduces Survivin protein levels and induces tumor cell apoptosis. Survivin-IN-1 is promising for research of malignant tumors such as lung cancer and breast cancer.
For research use only. We do not sell to patients.
- Formula: C47H66FN3O8
- Molecular Weight:820.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 820.04
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Formula C47H66FN3O8
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SMILES
O=C(N1CCN(C(NC2=CC=C(F)C=C2)=O)CC1)[C@@]34CC[C@@]5(C)[C@]6(C)CCC7[C@@](COC(C)=O)(C)[C@@H](OC(C)=O)[C@H](OC(C)=O)C[C@]7(C)C6CC=C5C3[C@@H](C)[C@H](C)CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)