1. Metabolic Enzyme/Protease
  2. NEDD8-activating Enzyme
  3. TAS4464 hydrochloride

TAS4464 hydrochloride 

Cat. No.: HY-128586A
Handling Instructions

TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.

For research use only. We do not sell to patients.

TAS4464 hydrochloride Chemical Structure

TAS4464 hydrochloride Chemical Structure

CAS No. : 1848959-11-4

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Description

TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].

IC50 & Target

IC50:0.955 nM (NAE)[1]

Clinical Trial
Molecular Weight

542.97

Formula

C₂₁H₂₄ClFN₆O₆S

CAS No.

1848959-11-4

SMILES

NC1=NC=NC2=C1C(C#CC3=C(F)C=CC=C3OCC)=CN2[[email protected]@H]4O[[email protected]](CNS(=O)(N)=O)[[email protected]@H](O)[[email protected]]4O.Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
TAS4464 hydrochloride
Cat. No.:
HY-128586A
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