TAT (47-57), TAMRA-labeled acetate
Based on 1 Customer Validation
TAT (47-57), TAMRA-labeled acetate is a fluorescently labeled cell-penetrating peptide derived from the HIV-1 transactivator of transcription (TAT). TAT (47-57), TAMRA-labeled acetate is conjugated to the red fluorescent dye carboxytetramethylrhodamine (TAMRA, with an absorption/emission wavelength of approximately 541/568 nM). TAT (47-57), TAMRA-labeled acetate can be used in studies related to cellular uptake, translocation and drug delivery.
For research use only. We do not sell to patients.
- Purity : 98.87%
- Formula: C89H138N34O18·xC2H4O2
- Molecular Weight:1972.27 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
In Vitro
The fluorescence signal of TAT (47-57), TAMRA-labeled acetate originates from TAMRA, while TAT provides cell-penetrating ability.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1972.27 (free base)
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Formula C89H138N34O18·xC2H4O2
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Color White to off-white
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SMILES
O=C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC1=CC=C(C=C1)O)NC(C2=CC(C([O-])=O)=C(C3=C4C=CC(N(C)C)=CC4=[O+]C5=C3C=CC(N(C)C)=C5)C=C2)=O.CC(O)=O.[x]
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Sequence
TAMRA-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg
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Sequence Shortening
TAMRA-YGRKKRRQRRR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)