Tetrahydrocorticosterone-d3-1
Tetrahydrocorticosterone-d3-1 is the d3-1-labeled Tetrahydrocorticosterone (HY-113422). Tetrahydrocorticosterone is a glucocorticoid. One of its active forms, 5α-Tetrahydrocorticosterone (HY-113364), exerts its effects by binding to the GC receptor and inhibiting inflammatory processes. Tetrahydrocorticosterone is naturally synthesized by the adrenal glands and plays a key role in regulating the metabolism of carbohydrates, proteins and fats.
For research use only. We do not sell to patients.
- Formula: C21H31D3O4
- Molecular Weight:353.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 68-42-8
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Molecular Weight 353.51
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Formula C21H31D3O4
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SMILES
C[C@@]12[C@](C(C([2H])([2H])O)=O)([2H])CC[C@@]1([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])[C@H](O)C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. McInnes KJ, et al. (May 2004). 5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor. The Journal of Biological Chemistry. 279 (22): 22908-12. [Content Brief]
[2]. Higashi T, et al. Studies on neurosteroids XXIII. Analysis of tetrahydrocorticosterone isomers in the brain of rats exposed to immobilization using LC-MS. Steroids. 2007;72(13):865-874. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tetrahydrocorticosterone-d3-1 Related Classifications
HY-113422S2 Related Classifications
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- Tetrahydrocorticosterone-d3-1
- Isotope-Labeled Compounds
- Endogenous Metabolite
- Glucocorticoid Receptor
- male rats
- glucocorticoid receptor
- HeLa cells
- hypothalamic-pituitary-adrenal axis
- adrenalectomized lean male Zucker rats
- H4IIE hepatoma cells
- rat liver homogenates
- rat hepatocytes
- phosphoenolpyruvate carboxykinase
- tyrosine aminotransferase
- Inhibitor
- inhibitor
- inhibit