Tetrahydrocorticosterone-d5
Based on 1 publication(s) in Google Scholar
Tetrahydrocorticosterone-d5 is the d5-labeled Tetrahydrocorticosterone (HY-113422). Tetrahydrocorticosterone is a glucocorticoid. One of its active forms, 5α-Tetrahydrocorticosterone (HY-113364), exerts its effects by binding to the GC receptor and inhibiting inflammatory processes. Tetrahydrocorticosterone is naturally synthesized by the adrenal glands and plays a key role in regulating the metabolism of carbohydrates, proteins and fats.
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- CAS No.: 2483831-29-2
- Formula: C21H29D5O4
- Molecular Weight:355.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Tetrahydrocorticosterone-d5
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2483831-29-2
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Unlabeled Cas 68-42-8
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Appearance Solid
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Molecular Weight 355.52
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Formula C21H29D5O4
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Color White to off-white
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SMILES
C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C([2H])([2H])[C@@](O)([2H])C([2H])([2H])C2)([H])[C@@](CC[C@@H]4C(CO)=O)([H])[C@]4(C)C[C@@H]3O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Metab
Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury. [Abstract]2024 Nov 5;36(11):2402-2418.e10. PMID: 39389061
Purity & Documentation
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Data Sheet (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. McInnes KJ, et al. (May 2004). 5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor. The Journal of Biological Chemistry. 279 (22): 22908-12. [Content Brief]
[2]. Higashi T, et al. Studies on neurosteroids XXIII. Analysis of tetrahydrocorticosterone isomers in the brain of rats exposed to immobilization using LC-MS. Steroids. 2007;72(13):865-874. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tetrahydrocorticosterone-d5 Related Classifications
HY-113422S Related Classifications
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- Tetrahydrocorticosterone-d5
- 2483831-29-2
- Isotope-Labeled Compounds
- Endogenous Metabolite
- Glucocorticoid Receptor
- male rats
- glucocorticoid receptor
- HeLa cells
- hypothalamic-pituitary-adrenal axis
- adrenalectomized lean male Zucker rats
- H4IIE hepatoma cells
- rat liver homogenates
- rat hepatocytes
- phosphoenolpyruvate carboxykinase
- tyrosine aminotransferase
- Inhibitor
- inhibitor
- inhibit