Thalidomide-6-F-5-pip-CHO
Based on 1 Customer Validation
Thalidomide-6-F-5-pip-CHO is a synthetic E3 ligase ligand-conjugate that can be used for the synthesis of PROTACs, such as DN1679 (HY-181035).
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 2505502-00-9
- Formula: C19H18FN3O5
- Molecular Weight:387.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2505502-00-9
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Appearance Solid
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Molecular Weight 387.36
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Formula C19H18FN3O5
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SMILES
O=CC1CCN(C2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2F)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (64.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5816 mL | 12.9079 mL | 25.8158 mL | 64.5394 mL |
| 5 mM | 0.5163 mL | 2.5816 mL | 5.1632 mL | 12.9079 mL | |
| 10 mM | 0.2582 mL | 1.2908 mL | 2.5816 mL | 6.4539 mL | |
| 15 mM | 0.1721 mL | 0.8605 mL | 1.7211 mL | 4.3026 mL | |
| 20 mM | 0.1291 mL | 0.6454 mL | 1.2908 mL | 3.2270 mL | |
| 25 mM | 0.1033 mL | 0.5163 mL | 1.0326 mL | 2.5816 mL | |
| 30 mM | 0.0861 mL | 0.4303 mL | 0.8605 mL | 2.1513 mL | |
| 40 mM | 0.0645 mL | 0.3227 mL | 0.6454 mL | 1.6135 mL | |
| 50 mM | 0.0516 mL | 0.2582 mL | 0.5163 mL | 1.2908 mL | |
| 60 mM | 0.0430 mL | 0.2151 mL | 0.4303 mL | 1.0757 mL |