2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl

Trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl is a synthetic target E3 ligase ligand-conjugate linker, which can be used to synthesize Azo-PROTAC-4C-trans (HY-180983). Azo-PROTAC-4C-trans is a BCR-ABL PROTAC degrader with anti-tumor activity.

For research use only. We do not sell to patients.

trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl

trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl Chemical Structure

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trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl Related Antibodies

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Description

Trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl is a synthetic target E3 ligase ligand-conjugate linker, which can be used to synthesize Azo-PROTAC-4C-trans (HY-180983). Azo-PROTAC-4C-trans is a BCR-ABL PROTAC degrader with anti-tumor activity[1].

Molecular Weight

588.01

Formula

C30H26ClN5O6
SMILES

O=C(C1=C2C=CC=C1NC(C3=CC=C(/N=N/C4=CC=C(OCCCCCl)C=C4)C=C3)=O)N(C(CC5)C(NC5=O)=O)C2=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-Cl Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

trans-Lenalidomide-CO-Ph-N2-Ph-O-C4-ClE3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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