TrkA-IN-6
TrkA-IN-6 (compound R48) is a hydrazone-like, selective inhibitor of tropomyosin kinase type A receptor kinase (TrkA). TrkA-IN-6 exhibited a higher cytotoxic effect on U87 GBM cells than Temozolomide (HY-17364), with an IC50 of 68.99 μM.
For research use only. We do not sell to patients.
- Formula: C16H13N3O5
- Molecular Weight:327.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
tropomyosin kinase receptor kinase type A (TrkA)[1]
Chemical Information
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Molecular Weight 327.29
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Formula C16H13N3O5
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SMILES
CC(/C(C(C1=CC=CC=C1)=O)=N\NC2=CC=C([N+]([O-])=O)C=C2O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)