2. Cell Cycle/DNA Damage Apoptosis Cytoskeleton
  3. Microtubule/Tubulin Apoptosis
  4. Tubulin polymerization-IN-56

Tubulin polymerization-IN-56 (compound 8l), an indazole derivative, is a potent tubulin polymerization inhibitor through interacting with the colchicine site, resulting in cell cycle arrest and cellular apoptosis. polymerization-IN-56 reduces cell migration and leads to more potent inhibition of tumor growth in vivo.

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Tubulin polymerization-IN-56 Chemical Structure

Tubulin polymerization-IN-56 Chemical Structure

CAS No. : 2966790-98-5

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Description

Tubulin polymerization-IN-56 (compound 8l), an indazole derivative, is a potent tubulin polymerization inhibitor through interacting with the colchicine site, resulting in cell cycle arrest and cellular apoptosis. polymerization-IN-56 reduces cell migration and leads to more potent inhibition of tumor growth in vivo[1].

Molecular Weight

411.88

Formula

C22H22ClN3O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC1=CC=C(C2=CC=C3C(N(C4=CC(OC)=C(OC)C(OC)=C4)N=C3)=C2)C=N1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Tubulin polymerization-IN-56 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-562966790-98-5Microtubule/TubulinApoptosisIndazoletubulin polymerizationcolchicine sitecell cycle arrestmigrationInhibitorinhibitorinhibit

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