Xamoterol hemifumarate (Standard)
Xamoterol hemifumarate (Standard) is the analytical standard of Xamoterol hemifumarate (HY-101327A). This product is intended for research and analytical applications. Xamoterol (Corwin; ICI 118587) hemifumarate is an orally active and selective β1-adrenoceptor partial agonist. Xamoterol hemifumarate acts as agonist at low sympathetic tone, antagonist at high sympathetic tone, with context-dependent cardiovascular effects including modulated heart rate, blood pressure, and cardiac output. Xamoterol hemifumarate can be used for the research of heart failure, postural hypotension, and ischemic heart disease.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 73210-73-8
- Formula: C20H29N3O9
- Molecular Weight:397.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 73210-73-8
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Molecular Weight 397.43
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Formula C20H29N3O9
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SMILES
O=C(N1CCOCC1)NCCNCC(O)COC2=CC=C(O)C=C2.O=C(O)/C=C/C(O)=O
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Synonyms
Corwin hemifumarate (Standard); ICI 118587 hemifumarate (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ikram H, et al. Xamoterol in severe heart failure. Lancet. 1990 Aug 25;336(8713):517-8. [Content Brief]
[2]. Malta E, et al. The in vitro pharmacology of xamoterol (ICI 118,587). Br J Pharmacol. 1985;85(1):179-187. [Content Brief]
[3]. Kowalski MT, et al. Comparison of the effects of xamoterol and isoprenaline on rat cardiac beta-adrenoceptors: studies of function and regulation. Br J Pharmacol. 1990;99(1):27-30. [Content Brief]
[4]. Mehlsen J, et al. Xamoterol, a new selective beta-1-adrenoceptor partial agonist, in the treatment of postural hypotension. Acta Med Scand. 1986;219(2):173-177. [Content Brief]
[5]. Hashimoto T, et al. The cardiovascular effects of xamoterol, a beta 1-adrenoceptor partial agonist, in healthy volunteers at rest. Br J Clin Pharmacol. 1986;21(3):259-265. [Content Brief]
[6]. Löfdahl CG, et al. Effects of xamoterol (ICI 118,587) in asthmatic patients. Br J Clin Pharmacol. 1984;18(4):597-601. [Content Brief]
[7]. Jennings G, et al. Cardioselectivity, kinetics, hemodynamics, and metabolic effects of xamoterol. Clin Pharmacol Ther. 1984;35(5):594-603. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Xamoterol hemifumarate (Standard) Related Classifications
HY-101327AR Related Classifications
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- Xamoterol hemifumarate (Standard)
- 73210-73-8
- Corwin hemifumarate (Standard)
- ICI 118587 hemifumarate (Standard)
- Adrenergic Receptor
- Reference Standards
- ischemic heart disease
- guinea-pig left atrial membranes
- heart failure
- progesterone-pretreated rat uterus
- β2-adrenoceptor
- rat atrial preparations
- cat left atria
- β1-adrenoceptor
- guinea pig
- postural hypotension
- Inhibitor
- inhibitor
- inhibit