2',2'-Difluorodeoxyuridine 5'-diphosphate
2',2'-Difluorodeoxyuridine 5'-diphosphate (dFdUDP) is an intracellular phosphorylated nucleotide metabolite formed from 2′,2′-Difluorodeoxyuridine (HY-138253) during exposure to Gemcitabine (HY-17026), and it shows low intracellular concentrations in peripheral blood mononuclear cells. 2',2'-Difluorodeoxyuridine 5'-diphosphate can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 1062136-12-2
- Formula: C9H12F2N2O11P2
- Molecular Weight:424.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2',2'-Difluorodeoxyuridine 5'-diphosphate , together with dFdUMP and dFdUTP, is characterized by low intracellular accumulation levels. This result raises doubts about whether dFdU nucleotides including dFdUDP are truly involved in the cytotoxic anti-tumor effect of Gemcitabine (HY-17026) in vivo[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1062136-12-2
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Molecular Weight 424.14
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Formula C9H12F2N2O11P2
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SMILES
O=C(C=CN1[C@H]2C(F)(F)[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O2)NC1=O
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Synonyms
dFdUDP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2',2'-Difluorodeoxyuridine 5'-diphosphate Related Classifications
HY-185842 Related Classifications
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