3-Amino ropivacaine

Cat. No.: HY-W742620 Pureza: 98.75%: Ficha de datos
COA

SDS
Instrucciones de manejo
FAQs
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3-Amino ropivacaine is a derivative of Ropivacaine (HY-B0563).

Para uso exclusivo en investigación. No vendemos a pacientes.

3-Amino ropivacaine Estructura química

No. CAS : 247061-08-1

Tamaño	Stock	Cantidad
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

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Descripciòn

3-Amino ropivacaine is a derivative of Ropivacaine (HY-B0563).

Peso molecular

289.42

Fòrmula

C₁₇H₂₇N₃O

No. CAS

247061-08-1

Appearance

Solid

Color

White to off-white

SMILES

CC(C(N)=CC=C1C)=C1NC([C@H]2N(CCCC2)CCC)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

DMSO : 50 mg/mL (172.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4552 mL	17.2759 mL	34.5519 mL
5 mM	0.6910 mL	3.4552 mL	6.9104 mL
10 mM	0.3455 mL	1.7276 mL	3.4552 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (8.64 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (8.64 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Pureza y Documentación

Purity: 98.75%

Select Batch:

Ficha de datos (243 KB) SDS (252 KB)

COA (248 KB) HNMR (253 KB) LCMS (324 KB)

Instrucciones de manejo (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4552 mL	17.2759 mL	34.5519 mL	86.3797 mL
	5 mM	0.6910 mL	3.4552 mL	6.9104 mL	17.2759 mL
	10 mM	0.3455 mL	1.7276 mL	3.4552 mL	8.6380 mL
	15 mM	0.2303 mL	1.1517 mL	2.3035 mL	5.7586 mL
	20 mM	0.1728 mL	0.8638 mL	1.7276 mL	4.3190 mL
	25 mM	0.1382 mL	0.6910 mL	1.3821 mL	3.4552 mL
	30 mM	0.1152 mL	0.5759 mL	1.1517 mL	2.8793 mL
	40 mM	0.0864 mL	0.4319 mL	0.8638 mL	2.1595 mL
	50 mM	0.0691 mL	0.3455 mL	0.6910 mL	1.7276 mL
	60 mM	0.0576 mL	0.2879 mL	0.5759 mL	1.4397 mL
	80 mM	0.0432 mL	0.2159 mL	0.4319 mL	1.0797 mL
	100 mM	0.0346 mL	0.1728 mL	0.3455 mL	0.8638 mL