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Cat. No.: HY-154131

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3-Deaza-xylouridine

3-Deaza-xylouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

Formula: C₁₀H₁₃NO₆
Molecular Weight:243.21

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

3-Deaza-xylouridine Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	CC₅₀	11 μM Compound: 1	Cytostatic activity against human CEM cells after 3 days by Coulter counting analysis Cytostatic activity against human CEM cells after 3 days by Coulter counting analysis	[PMID: 19378989]
L1210	CC₅₀	1.3 μM Compound: 1	Cytostatic activity against mouse L1210 cells after 2 days by Coulter counting analysis Cytostatic activity against mouse L1210 cells after 2 days by Coulter counting analysis	[PMID: 19378989]
Vero	CC₅₀	>200 μM Compound: 4	Cytotoxicity against african green monkey Vero cells after 3 days by neutral red dye method Cytotoxicity against african green monkey Vero cells after 3 days by neutral red dye method	[PMID: 23141915]
Vero	EC₅₀	>100 μM Compound: 4	Antiviral activity against Herpes simplex virus type 1 infected in Vero cells at 0.01 ID50/cells assessed as protection against virus-induced cytopathic effect after 3 days by neutral red dye method Antiviral activity against Herpes simplex virus type 1 infected in Vero cells at 0.01 ID50/cells assessed as protection against virus-induced cytopathic effect after 3 days by neutral red dye method	[PMID: 23141915]

Chemical Information

Molecular Weight 243.21
Formula C₁₀H₁₃NO₆
SMILES

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(C=C(O)C=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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