5-Bromo-UTP trisodium
5-Bromo-UTP (5-BrUTP) trisodium is a derivative of uridine triphosphate (UTP). 5-Bromo-UTP trisodium can be utilized by cells as a precursor for RNA synthesis. During transcription, it integrates into the newly synthesized RNA chain and replaces some UTP. 5-Bromo-UTP trisodium can be used to label newly synthesized RNA, thereby enabling high-resolution visualization of transcriptional sites and RNA transport.
For research use only. We do not sell to patients.
- Formula: C9H11BrN2Na3O15P3
- Molecular Weight:628.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 628.98
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Formula C9H11BrN2Na3O15P3
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C=C(Br)C(NC2=O)=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
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Synonyms
5-BrUTP trisodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Thiry M, et al. Dynamics and three-dimensional localization of ribosomal RNA within the nucleolus. RNA. 2000 Dec;6(12):1750-61. [Content Brief]
[2]. Cmarko D, et al. Ultrastructural analysis of nucleolar transcription in cells microinjected with 5-bromo-UTP. Histochem Cell Biol. 2000 Mar;113(3):181-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- 5-Bromo-UTP trisodium
- 5-BrUTP trisodium
- DNA/RNA Synthesis
- Nucleoside Antimetabolite/Analog
- 5-bromo-UTP
- nucleolus
- rRNA transcription
- immunoelectron microscopy
- confocal microscopy
- dense fibrillar component
- fibrillar center
- granular component
- pre-rRNA processing
- pulse-chase
- three-dimensional localization
- Inhibitor
- inhibitor
- inhibit