5-Hydroxy saxagliptin hydrochloride
5-Hydroxy saxagliptin hydrochloride is an active metabolite of Saxagliptin (HY-10285) and a potent and selective DPP-4 inhibitor. 5-Hydroxy saxagliptin hydrochloride has Ki values of 2.6 nM and 2.9 nM for humans and cynomolgus monkeys, respectively. 5-Hydroxy saxagliptin hydrochloride can be used in the research of type 2 diabetes mellitus.
For research use only. We do not sell to patients.
- Formula: C18H26ClN3O3
- Molecular Weight:367.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DPP-4 2.6 nM (Ki) |
DPP-8 2495 nM (Ki) |
DPP-9 423 nM (Ki) |
Chemical Information
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Molecular Weight 367.87
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Formula C18H26ClN3O3
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SMILES
O[C@@]1(C2)C[C@@]3([C@@H](C(N4[C@H](C#N)C[C@H]5[C@@H]4C5)=O)N)C[C@@](C[C@@H]2C3)(O)C1.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Hydroxy saxagliptin hydrochloride Related Classifications
HY-W741755A Related Classifications
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