5-Hydroxy saxagliptin-13C,d2-2 hydrochloride
5-Hydroxy saxagliptin-13C,d2-2 hydrochloride is the 13C- and deuterium labeled 5-Hydroxy saxagliptin hydrochloride. 5-Hydroxy saxagliptin hydrochloride is an active metabolite of Saxagliptin (HY-10285) and a potent and selective DPP-4 inhibitor. 5-Hydroxy saxagliptin hydrochloride has Ki values of 2.6 nM and 2.9 nM for humans and cynomolgus monkeys, respectively. 5-Hydroxy saxagliptin hydrochloride can be used in the research of type 2 diabetes mellitus.
For research use only. We do not sell to patients.
- CAS No.: 1572922-53-2
- Formula: C1713CH24D2ClN3O3
- Molecular Weight:370.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1572922-53-2
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Unlabeled Cas 1309934-04-0
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Molecular Weight 370.88
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Formula C1713CH24D2ClN3O3
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SMILES
O=C(N1[C@]2([H])[C@@](C[C@H]1C#N)([H])[13C]2([2H])[2H])[C@H](C34CC5(CC(C3)(CC(C5)C4)O)O)N.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Hydroxy saxagliptin-13C,d2-2 hydrochloride Related Classifications
HY-W741755S1 Related Classifications
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