5-Methyltetrahydropteroyltri-L-glutamate
5-Methyltetrahydropteroyltri-L-glutamate is an amino acid derivative. 5-Methyltetrahydropteroyltri-L-glutamate is present in the dried extract of Allium sativum (Hisar Garlic No. 17). 5-Methyltetrahydropteroyltri-L-glutamate participates in the remethylation of homocysteine to methionine via cobalamin-independent methionine synthase. 5-Methyltetrahydropteroyltri-L-glutamate is a biomarker associated with altered one-carbon transfer reactions in glioblastoma. 5-Methyltetrahydropteroyltri-L-glutamate can be used in glioblastoma-related research.
For research use only. We do not sell to patients.
- CAS No.: 133321-34-3
- Formula: C30H39N9O12
- Molecular Weight:717.68
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
5-Methyltetrahydropteroyltri-L-glutamate (24 h) accumulates in ZVp-treated U-251 glioblastoma cells, serving as an indicator of disrupted folate-mediated one-carbon metabolism associated with oxidative stress induced by the attenuated Zika virus prototype[2].
5-Methyltetrahydropteroyltri-L-glutamate interacts with LuxS in the thermophilic bacteria Meiothermus ruber and Caminibacter mediatlanticus, but not in Geobacillus thermoglucosidasius[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 133321-34-3
-
Molecular Weight 717.68
-
Formula C30H39N9O12
-
SMILES
CN1C2=C(NC(N)=NC2=O)NC[C@@H]1CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Methyltetrahydropteroyltri-L-glutamate Related Classifications
HY-N18390 Related Classifications
Powered by Bioz
- 5-Methyltetrahydropteroyltri-L-glutamate
- 133321-34-3
- Amino Acid Derivatives
- homocysteine
- LuxS
- Meiothermus ruber
- folate-mediated one-carbon metabolism
- one-carbon transfer reactions
- Allium sativum
- cobalamin-independent methionine synthase
- methionine
- glioblastoma cells
- U-251 glioblastoma cells
- Inhibitor
- inhibitor
- inhibit