7-Deaza-2',3'-dideoxyguanosine
Based on 1 Customer Validation
7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM.
For research use only. We do not sell to patients.
- Purity : 98.02%
- CAS No.: 111869-49-9
- Formula: C11H14N4O3
- Molecular Weight:250.25
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
HIV-1 |
Chemical Information
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CAS No. 111869-49-9
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Appearance Solid
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Molecular Weight 250.25
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Formula C11H14N4O3
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Color White to off-white
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SMILES
O=C1C2=C(N([C@@H]3O[C@H](CO)CC3)C=C2)NC(N)=N1
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Synonyms
7-Deaza-ddG
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (499.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9960 mL | 19.9800 mL | 39.9600 mL | 99.9001 mL |
| 5 mM | 0.7992 mL | 3.9960 mL | 7.9920 mL | 19.9800 mL | |
| 10 mM | 0.3996 mL | 1.9980 mL | 3.9960 mL | 9.9900 mL | |
| 15 mM | 0.2664 mL | 1.3320 mL | 2.6640 mL | 6.6600 mL | |
| 20 mM | 0.1998 mL | 0.9990 mL | 1.9980 mL | 4.9950 mL | |
| 25 mM | 0.1598 mL | 0.7992 mL | 1.5984 mL | 3.9960 mL | |
| 30 mM | 0.1332 mL | 0.6660 mL | 1.3320 mL | 3.3300 mL | |
| 40 mM | 0.0999 mL | 0.4995 mL | 0.9990 mL | 2.4975 mL | |
| 50 mM | 0.0799 mL | 0.3996 mL | 0.7992 mL | 1.9980 mL | |
| 60 mM | 0.0666 mL | 0.3330 mL | 0.6660 mL | 1.6650 mL | |
| 80 mM | 0.0500 mL | 0.2498 mL | 0.4995 mL | 1.2488 mL | |
| 100 mM | 0.0400 mL | 0.1998 mL | 0.3996 mL | 0.9990 mL |
7-Deaza-2',3'-dideoxyguanosine Related Classifications
HY-138592 Related Classifications
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