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  5. LEP(116-130)(mouse)

LEP(116-130)(mouse) is a synthetic leptin peptide fragment.

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カスタムペプチド

LEP(116-130)(mouse)

LEP(116-130)(mouse) 構造式

CAS 番号 : 258276-95-8

容量 価格（税別） 在庫状況 数量
5 mg $317 在庫あり
10 mg $515 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Based on 1 publication(s) in Google Scholar

LEP(116-130)(mouse) 関連抗体

Top Publications Citing Use of Products

  • 生物活性

  • プロトコル

  • 純度とドキュメンテーション

  • 参考文献

  • カスタマーレビュー

製品説明

LEP(116-130)(mouse) is a synthetic leptin peptide fragment.

体外実験

LEP-(116-130) (300 μM) is unable to inhibit AP-OB binding[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LEP(116-130)(mouse) 関連抗体
体内実験

LEP-(116-130) (1 mg, i.p.) results in a reduced rate of body weight gain in the presence of increased food intake compared with vehicle-injcted control mice. LEP-(116-130) significantly reduces blood glucose levels by appr 100 mg/dL. Administration of LEP-(116-130) to wild-type (+/+) C57BLKS/J-m mice for 4 or 7 days has no effect on their ability to thermoregulate[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1560.73

分子式

C64H109N19O24S
CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2
Sequence Shortening

SCSLPQTSGLQKPES-NH2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : ≥ 100 mg/mL (64.07 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6407 mL 3.2036 mL 6.4073 mL
5 mM 0.1281 mL 0.6407 mL 1.2815 mL
10 mM 0.0641 mL 0.3204 mL 0.6407 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (64.07 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション
参考文献
動物実験
[1]

Blood is drawn from the tail vein of each mouse 2 h before the onset of the dark period at the beginning of the study (day 0) and after 2, 4, and 6 days of treatment with 1 mg/day i.p. LEP-(116-130). Blood glucose levels are determined with a Glucometer Elite blood glucose monitor. After 4 and 7 days of treatment with 1 mg/day i.p. LEP-(116-130), sensitivity to cold is examined by placing the mice without food or water in a cold room with an ambient temperature of 4°C. Body temperature is measured with a rectal probe every hour for 4 h.

MedChemExpress (MCE) はこれらの方法の精度を確認していません。 こちらは参照専用です。
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.6407 mL 3.2036 mL 6.4073 mL 16.0181 mL
5 mM 0.1281 mL 0.6407 mL 1.2815 mL 3.2036 mL
10 mM 0.0641 mL 0.3204 mL 0.6407 mL 1.6018 mL
15 mM 0.0427 mL 0.2136 mL 0.4272 mL 1.0679 mL
20 mM 0.0320 mL 0.1602 mL 0.3204 mL 0.8009 mL
25 mM 0.0256 mL 0.1281 mL 0.2563 mL 0.6407 mL
30 mM 0.0214 mL 0.1068 mL 0.2136 mL 0.5339 mL
40 mM 0.0160 mL 0.0801 mL 0.1602 mL 0.4005 mL
50 mM 0.0128 mL 0.0641 mL 0.1281 mL 0.3204 mL
60 mM 0.0107 mL 0.0534 mL 0.1068 mL 0.2670 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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LEP(116-130)(mouse) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LEP(116-130)(mouse)258276-95-8OthersInhibitorinhibitorinhibit

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製品名:
LEP(116-130)(mouse)
製品番号:
HY-P1027
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