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Nastorazepide

HY-17617

(Z-360)

Nastorazepide

Nastorazepide Chemical Structure

Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity.

Size Price Stock Quantity
10 mM * 1 mL in DMSO $401 In-stock
5 mg $350 In-stock
10 mg $500 In-stock
50 mg $1500 In-stock
100 mg $2100 In-stock
200 mg Get quote
500 mg Get quote
Size Price Stock Quantity
10 mM * 1 mL in DMSO €393 In-stock
5 mg €343 In-stock
10 mg €490 In-stock
50 mg €1470 In-stock
100 mg €2058 In-stock
200 mg Get quote
500 mg Get quote

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Product name: Nastorazepide
Cat. No.: HY-17617

Nastorazepide Data Sheet

  • Network Version

    DataSheet

Related Compound Libraries

Biological Activity of Nastorazepide

Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity.
Target:CCK-2
in vitro: Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells. Check for active clinical trials or closed clinical trials using this agent.
in vivo: Z-360 is a novel orally active CCK-2/gastrin receptor antagonist, significantly inhibits the growth of subcutaneous xenografts of human pancreatic tumor cells in mice, and that Z-360 combined with gemcitabine prolonged survival in a pancreatic carcinoma orthotopic xenograft mice.

Protocol (Extracted from published papers and Only for reference)

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Chemical Information

M.Wt 520.62 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Formula C₂₉H₃₆N₄O₅
CAS No 209219-38-5
Solvent & Solubility

DMSO: ≥ 32 mg/mL

Preparing Stock Solutions

1 mg 5 mg 10 mg
1 mM 1.9208 mL 9.6039 mL 19.2079 mL
5 mM 0.3842 mL 1.9208 mL 3.8416 mL
10 mM 0.1921 mL 0.9604 mL 1.9208 mL

References on Nastorazepide

Inhibitor Kit