1. Natural Products
  2. Others

Others

Others (522):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-10219
    Rapamycin 53123-88-9 99.93%
    Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator.
    Rapamycin
  • HY-12320
    Cycloheximide 66-81-9 99.45%
    Cycloheximide (Naramycin A) is an eukaryote protein synthesis inhibitor, with IC50s of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively.
    Cycloheximide
  • HY-15142
    Doxorubicin hydrochloride 25316-40-9 99.47%
    Doxorubicin hydrochloride is a cytotoxic anthracycline antibiotic for the treatment of multiple cancers. The possible mechanisms by which doxorubicin acts in the cancer cell are intercalation into DNA and disruption of topoisomerase-II-mediated DNA repair.
    Doxorubicin hydrochloride
  • HY-17559
    Actinomycin D 50-76-0 99.89%
    Actinomycin D inhibits DNA repair with an IC50 of 0.42 μM.
    Actinomycin D
  • HY-18739
    Phorbol 12-myristate 13-acetate 16561-29-8 99.08%
    Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is an activator of SphK through protein kinase C (PKC) activation.
    Phorbol 12-myristate 13-acetate
  • HY-13316
    Mitomycin C 50-07-7 99.45%
    Mitomycin C is an antitumor drug and antibiotic that shows extraordinary ability to inhibit DNA synthesis. Mitomycin C is a DNA cross-linking agent, which induces DNA damaging.
    Mitomycin C
  • HY-100558
    Bafilomycin A1 88899-55-2 >99.0%
    Bafilomycin A1, a macrolide antibiotic isolated from the Streptomyces species, is a specific inhibitor of vacuolar-type H+ ATPase (V-ATPase). Bafilomycin A1 inhibits autophagy.
    Bafilomycin A1
  • HY-13948
    Angiotensin II human 4474-91-3 99.96%
    Angiotensin II human is a vasoconstrictor that acts on the AT1 and the AT2 receptor.
    Angiotensin II human
  • HY-B1743A
    Puromycin Dihydrochloride 58-58-2 99.87%
    Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.
    Puromycin Dihydrochloride
  • HY-15141
    Staurosporine 62996-74-1 99.98%
    Staurosporine is a potent and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively.
    Staurosporine
  • HY-15144
    Trichostatin A 58880-19-6 99.53%
    Trichostatin A is a potent and specific inhibitor of HDAC class I/II, with an IC50 value of 1.8 nM for HDAC.
    Trichostatin A
  • HY-B0579
    Cyclosporin A 59865-13-3 >98.0%
    Cyclosporin A is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM.
    Cyclosporin A
  • HY-A0190
    Ceruletide 17650-98-5 99.96%
    Ceruletide, a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, is a potent cholecystokinetic agent, and acts as a cholecystokinin receptor agonist.
    Ceruletide
  • HY-16592
    Brefeldin A 20350-15-6 99.79%
    Brefeldin A is a specific inhibitor of protein trafficking which blocks the protein transport from the endoplasmic reticulum to the Golgi complex.
    Brefeldin A
  • HY-A0098
    Tunicamycin 11089-65-9 99.69%
    Tunicamycin is a N-acetylglucosamine containing antibiotic from Streptomyces lysosuperijkus which inhibits protein glycosylation.
    Tunicamycin
  • HY-B0215
    Acetylcysteine 616-91-1 >98.0%
    Acetylcysteine is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor.
    Acetylcysteine
  • HY-13756
    Tacrolimus 104987-11-3 98.46%
    Tacrolimus is a macrocyclic lactone with potent immunosuppressive properties. Tacrolimus binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase.
    Tacrolimus
  • HY-14649
    Retinoic acid 302-79-4 98.36%
    Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.
    Retinoic acid
  • HY-13753
    Streptozocin 18883-66-4 99.58%
    Streptozocin is a potent DNA-methylating agent, with IC50s of 11.7, 904 and 1024 μg/mL in HL60, K562 and C1498 cells respectively.
    Streptozocin
  • HY-10002
    Calcitriol 32222-06-3 99.81%
    Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
    Calcitriol