147-94-4
Chemical Structure
Cytarabine
Synonym(s): Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C
- CAS No.: 147-94-4
- Formula:C9H13N3O5
- Molecular Weight:243.22
IUPAC Name: 4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
InChIKey: UHDGCWIWMRVCDJ-CCXZUQQUSA-N
SMILES: O=C1N=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O2)N
Biological Activity: Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.
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Cytarabine | 99.98% | Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity. | ||||||||||||||||||||
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Cytarabine (Standard) | 99.98% | Cytarabine (Standard) is the analytical standard of Cytarabine. This product is intended for research and analytical applications. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity. | ||||||||||||||||||||
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Cytarabine-13C3 | Cytarabine-13C3 (Cytosine β-D-arabinofuranoside-13C3) is 13C labeled Cytarabine. | |||||||||||||||||||||
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Cytarabine-13C,15N2 | Cytarabine-13C,15N2 (Cytosine β-D-arabinofuranoside-13C,15N2) is the 13C- and 15N-labeled Cytarabine (HY-13605). Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity. | |||||||||||||||||||||
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Cytarabine-d2 | 98.0% | Cytarabine-d2 is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. | ||||||||||||||||||||
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