Cytarabine (Standard)
Based on 1 Customer Validation
Cytarabine (Standard) is the analytical standard of Cytarabine. This product is intended for research and analytical applications. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.
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- Pureté : 99.98%
- CAS No.: 147-94-4
- Formule: C9H13N3O5
- Masse moléculaire:243.22
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-13605
CytarabineDNA Synthesis Inhibitor -
HY-13062A
DaunorubicinTopoisomerase II Inhibitor -
HY-17393
CarboplatinDNA Synthesis Inhibitor -
HY-B0069
FludarabineDNA Synthesis Inhibitor -
HY-17422
AcyclovirHSV Inhibitor -
HY-17026
GemcitabineDNA Synthesis Inhibitor -
HY-A0004
DecitabineDNMT Inhibitor -
HY-13605A
Cytarabine hydrochlorideDNA Synthesis Inhibitor -
HY-A0005
ClofarabineRibonucleotide Reductase Inhibitor -
HY-B0003
Gemcitabine hydrochlorideDNA Synthesis Inhibitor -
HY-B0016
CapecitabineDNA/RNA Synthesis Inhibitor -
HY-B1449
UridineNucleoside
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 147-94-4
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Appearance Solid
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Masse moléculaire 243.22
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Formule C9H13N3O5
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Color White to off-white
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SMILES
O=C1N=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O2)N
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Synonyms
Cytosine β-D-arabinofuranoside (Standard); Cytosine Arabinoside (Standard); Ara-C (Standard)
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Tobias, S.C. and R.F. Borch, Synthesis and biological evaluation of a cytarabine phosphoramidate prodrug. Mol Pharm, 2004. 1(2): p. 112-6. [Content Brief]
[2]. Besirli, C.G., et al. Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death Differ, 2003. 10(9): p. 1045-58. [Content Brief]
[3]. Yamauchi, H., et al., Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced trophoblastic cell apoptosis and impaired proliferation in rat placenta. Biol Reprod, 2004. 70(6): p. 1762-7. [Content Brief]
[4]. Richel, D.J., et al., Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia. Br J Cancer, 1988. 58(6): p. 730-3. [Content Brief]
[5]. Shepshelovich D, et al. Pharmacodynamics of cytarabine induced leucopenia: a retrospective cohort study. Br J Clin Pharmacol. 2015 Apr;79(4):685-91. [Content Brief]
[6]. Renis HE. Antiviral activity of cytarabine in herpesvirus-infected rats. Antimicrob Agents Chemother. 1973 Oct;4(4):439-44. [Content Brief]
[7]. Gruffaz M, Zhou S, Vasan K, et al. Repurposing Cytarabine for Treating Primary Effusion Lymphoma by Targeting Kaposi's Sarcoma-Associated Herpesvirus Latent and Lytic Replications. mBio. 2018;9(3):e00756-18. Published 2018 May 8. [Content Brief]
[8]. Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cytarabine (Standard) Related Classifications
HY-13605R Related Classifications
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