Alkanna tinctoria (L.) Tausch
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Alkanna tinctoria (L.) Tausch (1)
Angelylalkannin
Cat. No.: HY-126596
CAS No.: 69175-72-0
- Formula: C21H22O6
- Molecular Weight: 370.40
Angelylalkannin is a naphthoquinone compound isolated from the root of Alkanna tinctoria. Angelylalkannin showed significant inhibitory effects in the antiproliferative effect test on human colon cancer cells HCT-116 and SW-480. The median inhibitory concentration (IC50) of Angelylalkannin was 4.76 mM for HCT-116 cells and 7.03 mM for SW-480 cells. Like alkannin, Angelylalkannin can arrest the cell cycle in the G1 phase and induce apoptosis at a concentration of 1-10 mM.
