2. Natural Products
  3. Plants
  4. Leguminosae
  5. Genista ephedroides DC.

Genista ephedroides DC.

Genista ephedroides DC. (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1073
    Wighteone 51225-30-0 98.71%
    Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFRL858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFRL858R/T790M mutation, and fungal infections.
    Wighteone
  • HY-N3476
    Isokaempferide 1592-70-7 99.88%
    Isokaempferide is a flavonoid can be isolated from the aerial parts of Genista ephedroides.
    Isokaempferide