2. 天然物
  3. Plants
  4. Saxifragaceae
  5. Penthorum chinense Pursh

Penthorum chinense Pursh

Penthorum chinense Pursh (7):

製品番号 製品名 CAS 番号 純度 構造式
  • HY-N5084
    Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside 205370-59-8 98.92%
    Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside is a TRPV1 antagonist and HDAC7 inhibitor. Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside blocks TRPV1-mediated calcium influx, suppresses phosphorylation of p65, IκBα, p38, JNK, and ERK1/2, inhibiting NF-κB and MAPK signaling cascades. Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside reduces production and gene expression of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside exhibits potent analgesic activity, elevates thermal pain threshold and mechanical pain threshold in murine models. Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside restores CD8+ T cell infiltration into bladder cancer tumors and improves bladder cancer immunotherapy efficacy. Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can be used for the researches of painand bladder cancer.
    Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside
  • HY-N6616
    Pinocembrin-7-O-β-D-glucopyranoside

    Pinocembrin-7-O-β-D-glucopyranoside

    		75829-43-5 99.87%
    Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-β-D-Glucoside) is is a flavanone that enhances lipid peroxidation.
    Pinocembrin-7-O-β-D-glucopyranoside
  • HY-N16983
    2',4',6'-Trihydroxydihydrochalcone-4'-O-(3''-O-galloyl)glucoside 1885097-49-3
    2',4',6'-Trihydroxydihydrochalcone-4'-O-(3''-O-galloyl)glucoside is a natural chalcone.
    2',4',6'-Trihydroxydihydrochalcone-4'-O-(3''-O-galloyl)glucoside
  • HY-N16980
    (7'E,8S)-2',4,8-Trihydroxy-3-methoxy-2,4'-epoxy-8,5'-neolign-7'-en-7-one 2292113-33-6
    (7'E,8S)-2',4,8-Trihydroxy-3-methoxy-2,4'-epoxy-8,5'-neolign-7'-en-7-one (compound 4) is a novel neolignan anti-inflammatory agent. (7'E,8S)-2',4,8-Trihydroxy-3-methoxy-2,4'-epoxy-8,5'-neolign-7'-en-7-one has an IC50 of 25.2 μM against TGF-β-induced hepatic stellate cells (HSC-T6). (7'E,8S)-2',4,8-Trihydroxy-3-methoxy-2,4'-epoxy-8,5'-neolign-7'-en-7-one may be related to blocking excessive cell proliferation in the process of liver fibrosis and can be used in the study of liver fibrosis-related diseases. (7'E,8S)-2',4,8-Trihydroxy-3-methoxy-2,4'-epoxy-8,5'-neolign-7'-en-7-one can be naturally extracted from the dried aerial parts of Penthorum chinense Pursh.
    (7'E,8S)-2',4,8-Trihydroxy-3-methoxy-2,4'-epoxy-8,5'-neolign-7'-en-7-one
  • HY-N6616R
    Pinocembrin-7-O-β-D-glucopyranoside (Standard) 75829-43-5
    Pinocembrin-7-O-β-D-glucopyranoside (Standard) is the analytical standard of Pinocembrin-7-O-β-D-glucopyranoside. This product is intended for research and analytical applications. Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-β-D-Glucoside) is is a flavanone that enhances lipid peroxidation.
    Pinocembrin-7-O-β-D-glucopyranoside (Standard)
  • HY-N13117
    Pinocembrin 7-O-[4′′,6′′-(S)-HHDP]-β-D-glucoside 205370-58-7
    Pinocembrin 7-O-[4′′,6′′-(S)-HHDP]-β-D-glucoside (compound 3) is a polyphenol that has weak antiproliferative activity in PDGF-induced HSC-T6 cells (IC50: 200 μM).
    Pinocembrin 7-O-[4′′,6′′-(S)-HHDP]-β-D-glucoside
  • HY-N6956
    5-MethoxyPinocembroside 1450878-89-3
    5-MethoxyPinocembroside is a flavonoid isolated from Penthorumchinense Pursh. 5-MethoxyPinocembroside has demonstrated a specific pharmacological effect against hepatic steatosis.
    5-MethoxyPinocembroside