2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose
2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose is a novel polyphenol/ellagitannin-type glucoside. 2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose mediates antiproliferative effects via platelet-derived growth factor (PDGF)-induced hepatic stellate cells. 2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose can be used for the research of hepatic fibrosis.
For research use only. We do not sell to patients.
- CAS No.: 1781226-44-5
- Formula: C28H24O17
- Molecular Weight:632.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose Chemical Structure](https://file.medchemexpress.com/product_pic/hy-n8032.gif "Click to View 2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose Chemical Structure")
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HSC-T6 | IC50 |
12.7 μM
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Antiproliferative activity against PDGF-induced rat hepatic stellate HSC-T6 cells assessed as reduction in cell proliferation incubated for 24 hrs by MTT assay.
Antiproliferative activity against PDGF-induced rat hepatic stellate HSC-T6 cells assessed as reduction in cell proliferation incubated for 24 hrs by MTT assay.
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25076141 |
In Vitro
2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose (Compound 2) moderately inhibits PDGF-induced proliferation of HSC-T6 cells after 24 h, with an IC50 value of 12.7 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1781226-44-5
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Molecular Weight 632.48
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Formula C28H24O17
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SMILES
CC(C1=C(O)C=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](COC3=O)O2)OC(C4=CC(O)=C(O)C(O)=C4C5=C(O)C(O)=C(O)C=C53)=O)O)O)C=C1O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2,6-Dihydroxyacetophenone-4-O-[4,6-(S)-hexahydroxydiphenoyl]-β-D-glucose Related Classifications
HY-N8032 Related Classifications
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