Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2499)
Related Products (2499)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Lunarine
0 ImagesCat. No.: HY-129278CAS No.: 24185-51-1Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with Ki of 304 μM.
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Symetine dihydrochloride
0 ImagesCat. No.: HY-101590ACAS No.: 5585-62-6Synonyms: L 16726 dihydrochloride
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Sphynolactone-7
0 ImagesCat. No.: HY-125284CAS No.: 2305752-57-0Synonyms: SPL7Sphynolactone-7 (SPL7) is an active site-targeting and selective strigolactone receptor (ShHTL7) agonist. Sphynolactone-7 is effective for reducing Striga parasitism without impinging on host strigolactone-related processes.
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SID 24785302
0 ImagesCat. No.: HY-169728CAS No.: 378197-09-2SID 24785302 is a hexokinase inhibitor with antiparasitic activity. SID 24785302 exhibits activity against T. brucei and Leishmania. SID 24785302 can be used for the research of mitochondrial DNA disorders and parasitic infection.
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Pyrantel
0 ImagesCat. No.: HY-12641ACAS No.: 15686-83-6Pyrantel is an orally active antiparasitic agent. Pyrantel induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel eliminates both immature and mature endoparasites in horses. Pyrantel can be used in research related to parasitic infections.
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SL-IN-1
0 ImagesCat. No.: HY-162522SL-IN-1 (Compound C6) is an inhibitor for plant hormone steroid lactones receptor (SL receptor). SL-IN-1 promotes rice tillering, inhibits the germination of the root parasite P. aegyptiaca seeds (IC50 is 82.8 µM), delays dark-induced senescence of rice leaves, and protects the leaf membrane from lipid peroxidation.
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Trypanothione synthetase-IN-3
0 ImagesCat. No.: HY-151151CAS No.: 1314875-96-1Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum.
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Diamfenetide (Standard)
0 ImagesCat. No.: HY-119893RCAS No.: 36141-82-9Diamfenetide (Standard) is the analytical standard of Diamfenetide. This product is intended for research and analytical applications. Diamfenetide is used for the study of Fasciola hepatica infections in vitro.?Diamfenetide?leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica.
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Cysteine protease inhibitor-3
0 ImagesCat. No.: HY-155054CAS No.: 3051934-95-0Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC50s of 0.74 μM, 1.05 μM, 3.5 μM, and 4.9 μM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites.
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Efavirenz (Standard)
0 ImagesSynonyms: DMP 266 (Standard); EFV (Standard); L-743726 (Standard)Efavirenz (Standard) is the analytical standard of Efavirenz. This product is intended for research and analytical applications. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
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Hederacolchiside A1 (Standard)
0 ImagesCat. No.: HY-N6950RCAS No.: 106577-39-3Hederacolchiside A1 (Standard) is the analytical standard of Hederacolchiside A1. This product is intended for research and analytical applications. Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro.
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Antileishmanial agent-2
0 ImagesCat. No.: HY-132905CAS No.: 2863687-18-5Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells.
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Antitrypanosomal agent 2
0 ImagesCat. No.: HY-136200CAS No.: 475626-30-3Antitrypanosomal agent 2 is a potent and selective trypanosoma brucei inhibitor.
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LC-61
0 ImagesCat. No.: HY-180130CAS No.: 2195159-10-3LC-61 is a potent antileishmanial agent with an IC50 of 0.076 µM against intracellular L. infantum.
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Nifuratel (Standard)
0 ImagesSynonyms: NF 113 (Standard); SAP 113 (Standard); Methylmercadone (Standard)Nifuratel (Standard) is the analytical standard of Nifuratel. This product is intended for research and analytical applications. Nifuratel (NF 113, SAP 113) is a broad-spectrum antibiotic with activity against bacteria, fungi and trichomonas.
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Anti-Trypanosoma cruzi agent-8
0 ImagesCat. No.: HY-181516Anti-Trypanosoma cruzi agent-8 is an anti-Trypanosoma agent and also a Trypanosoma cruzi trypanothione reductase (TcTR) inhibitor, with an IC50 of 3.9 μM against TcTR. Anti-Trypanosoma cruzi agent-8 functionally inhibits the enzymatic activity of TcTR. Anti-Trypanosoma cruzi agent-8 exhibits trypanocidal activity against intracellular Trypanosoma cruzi amastigotes.
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PDEB1-IN-1
0 ImagesCat. No.: HY-116045CAS No.: 1622300-88-2PDEB1-IN-1 (Compound 12b) is the derivative of Cilomilast (HY-10790), and serves as an inhibitor for TryPanosoma Brucei PDEB1 (TbrPDEB1) with an IC50 of 0.95 μM. PDEB1-IN-1 inhibits the proliferation of T. Brucei with an EC50 of 26 μM.
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TgCDPK1-IN-1
0 ImagesCat. No.: HY-184426TgCDPK1-IN-1 is an orally active, blood-brain barrier-permeable TgCDPK1 inhibitor (IC50 = 15.7 nM) with antiparasitic activity against Toxoplasma gondii. TgCDPK1-IN-1 inhibits Src and TgCDPKG128M. TgCDPK1-IN-1 cures acute toxoplasmosis in immunocompetent mice and prolongs the survival of immunocompromised mice. TgCDPK1-IN-1 is applicable for research related to toxoplasmosis.
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KDU731 (Standard)
0 ImagesCat. No.: HY-103583RCAS No.: 1610610-48-4KDU731 (Standard) is the analytical standard of KDU731 (HY-103583). This product is intended for research and analytical applications. KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo. KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety.
