15686-83-6
15686-83-6
Chemical Structure
Pyrantel
- CAS No.: 15686-83-6
- Formula:C11H14N2S
- Molecular Weight:206.31
IUPAC Name: (E)-1-methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine
InChIKey: YSAUAVHXTIETRK-AATRIKPKSA-N
SMILES: CN1CCCN=C1/C=C/C2=CC=CS2
Biological Activity: Pyrantel is an orally active antiparasitic agent. Pyrantel induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel eliminates both immature and mature endoparasites in horses. Pyrantel can be used in research related to parasitic infections[1][2][3].
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Pyrantel | Pyrantel is an orally active antiparasitic agent. Pyrantel induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel eliminates both immature and mature endoparasites in horses. Pyrantel can be used in research related to parasitic infections. | |||||||||||||||||||||
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References
- [1]. Tritten L, et al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS neglected tropical diseases. 2011 Dec;5(12):e1457. [Content Brief]
- [2]. Martin RJ, et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. International journal for parasitology. 2004 Aug;34(9):1083-90. [Content Brief]
- [3]. Lyons ET, et al. Critical test of three salts of pyrantel against internal parasites of the horse. Am J Vet Res. 1974 Dec;35(12):1515-22. [Content Brief]
