3051934-95-0
3051934-95-0
Chemical Structure
Cysteine protease inhibitor-3
- CAS No.: 3051934-95-0
- Formula:C26H22ClF2N3O
- Molecular Weight:465.92
InChIKey: VBYITYHKLOIIBW-UHFFFAOYSA-N
SMILES: OC1=CC=CC=C1C(C2=CC(F)=C(F)C=C2)N(CC3)CCN3C4=CC=NC5=CC(Cl)=CC=C54
Biological Activity: Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC50s of 0.74 μM, 1.05 μM, 3.5 μM, and 4.9 μM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites[1].
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Cysteine protease inhibitor-3 | Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC50s of 0.74 μM, 1.05 μM, 3.5 μM, and 4.9 μM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites. | |||||||||||||||||||||
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