2. Signaling Pathways
  3. GPCR/G Protein
  4. Chemerin Receptor
  5. Chemerin Receptor Ligand

Chemerin Receptor Ligand

Chemerin Receptor Isoform Comparison

Chemerin Receptor Ligand (1):

Cat. No. Product Name Effect Purity
  • HY-P6442
    Chemerin15
    		Ligand 99.65%
    Chemerin15 is an anti-inflammatory peptide derived from Chemerin. Chemerin15 binds to ChemR23. Chemerin15 inhibits TNFα-induced activation of Syk, ERK and Src kinases. Chemerin15 increases the expression of p-p38 mRNA and protein. Chemerin15 mediates phagocytosis, resolution of inflammation, CD62L shedding and downregulation of PSGL-1 expression in macrophages and microglia. Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury via ChemR23. Chemerin15 enhances microglial phagocytosis, thereby alleviating cerebral ischemia-reperfusion injury.