2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Dihydrofolate reductase (DHFR)
  5. Dihydrofolate reductase (DHFR) Substrate

Dihydrofolate reductase (DHFR) Substrate

Dihydrofolate reductase (DHFR) Substrate (1):

Cat. No. Product Name Effect Purity
  • HY-137129
    10-Formyl-7,8-dihydrofolic acid
    		Substrate
    10-Formyl-7,8-dihydrofolic acid is a biologically active folic acid and growth promoter. 10-Formyl-7,8-dihydrofolic acid serves as a substrate for aminoimidazolecarboxamide ribonucleotide transformylase and dihydrofolate reductase (DHFR) to support catalytic reactions (with detection wavelengths of 552 nm and 340 nm, respectively). 10-Formyl-7,8-dihydrofolic acid not only promotes the growth of leukemia cells, but also effectively reverses the growth inhibition induced by antifolate drugs under folate-deficient conditions. 10-Formyl-7,8-dihydrofolic acid can be used in the research of leukemia.