Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (3989)
Related Products (3989)
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Hydrocarbon chain derivative 1
0 ImagesCat. No.: HY-U00332CAS No.: 300762-25-8Synonyms: 6,6'-Oxybis[2,2-dimethyl-1-hexanol]Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis.
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Antiasthmatic Compound 1
0 ImagesCat. No.: HY-U00409CAS No.: 63768-49-0Antiasthmatic Compound 1 is an antiasthmatic agent, which has the potential for allergic asthma treatment.
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Glycerol derivative 1
0 ImagesCat. No.: HY-U00378CAS No.: 128400-55-5Glycerol derivative 1 is a Glycerol derivative extracted from patent EP 672415 A1, compound (1).
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Deloxolone
0 ImagesCat. No.: HY-U00278CAS No.: 68635-50-7Synonyms: (3β,20β)-3-(3-Carboxy-1-oxopropoxy)olean-9(11)-en-29-oic acidDeloxolone has the potential for inflammatory, ischemic and proliferative diseases treatment.
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Anti-hypertensive sulfonanilide 1
0 ImagesCat. No.: HY-U00301CAS No.: 129280-22-4Anti-hypertensive sulfonanilide 1 is a potent antihypertensive agent extracted from patent EP0338793A2, compound XVIIIa,b*, example No.1.
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Antiulcer Agent 1
0 ImagesCat. No.: HY-U00122CAS No.: 76001-09-7Antiulcer Agent 1 is a 2-(3,4-dimethoxyphenyl)ethylamine derivative for oral administration at an exploratory stage of new agent development.
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Carbazole derivative 1
0 ImagesCat. No.: HY-U00323CAS No.: 164914-28-7Synonyms: 2-Fluoro-7-[(3-pyridinyl)methyl]-9H-carbazoleCarbazole derivative 1 is a carbazole derivative which can be used to reduce androgen or oestrogen levels in mammals, including humans.
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Urinary Incontinence-Targeting Compound 1
0 ImagesCat. No.: HY-U00357CAS No.: 137315-05-0Urinary Incontinence-Targeting Compound 1 is a sulfonanilide derivative, used in the research of urinary incontinence.
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Heterocyclyl carbamate derivative 1
0 ImagesCat. No.: HY-101831CAS No.: 168830-01-1Heterocyclyl carbamate derivative 1 is a heterocyclyl carbamate derivative that may be used for the research of inflammatory and neurological diseases.
