2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10678):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-21622S
    Thiomorpholine 1,1-dioxide-d8
    		98.0%
    Thiomorpholine 1,1-dioxide-d8 (Thiomorpholine-2,6-dione-d8) is a deuterium labeled Thiomorpholine 1,1-dioxide.
    Thiomorpholine 1,1-dioxide-d<sub>8</sub>
  • HY-W707517
    Famotidine-d4
    Famotidine-d4 (MK-208-d4) is deuterium labeled Famotidine. Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
    Famotidine-d<sub>4</sub>
  • HY-D0187S6
    L-Glutathione reduced-15N
    L-Glutathione reduced-15N (GSH-15N; γ-L-Glutamyl-L-cysteinyl-glycine-15N) is 15N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.
    L-Glutathione reduced-<sup>15</sup>N
  • HY-125678S
    Jasmine lactone-d2
    Jasmine lactone-d2 is deuterated labeled Jasmine lactone (HY-125678). Jasmine lactone, a volatile substance produced by plants under stress, has a strong odor and is known for its unique jasmine-like floral and fruity scent which is very popular in tea, especially in oolong and black tea. The biosynthesis mechanism of Jasmine lactone in tea is regulated by various stresses, including mechanical damage and low temperature stress. Continuous mechanical damage and low temperature and mechanical damage can enhance the accumulation of Jasmine lactone in tea.
    Jasmine lactone-d<sub>2</sub>
  • HY-103315S
    Bepridil-d5 hydrochloride
    Bepridil-d5 (hydrochloride) (CERM 1978-d5) is deuterium labeled Bepridil hydrochloride. Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.
    Bepridil-d<sub>5</sub> hydrochloride
  • HY-W021008S
    Sotolone-d2
    Sotolone-d2 (Dimethylhydroxyfuranone-d2) is deuterated labeled Sotolone. Sotolone is an activator of the human olfactory receptor OR8D1. Sotolone activates the human olfactory receptor OR8D1, with EC50 values of 84.98 μM and 167.2 μM for its S-enantiomer and R-enantiomer, respectively. Sotolone has unique aroma profiles: (R)-sotolone exhibits smoky, burnt, herbal and grassy notes; (S)-sotolone presents sweet, milky, sour and nutty notes. Sotolone also acts as an antifungal agent, showing moderate inhibitory activity against Magnaporthe oryzae in vitro.
    Sotolone-d<sub>2</sub>
  • HY-113331S1
    Thromboxane B2-d9
    Thromboxane B2-d9 is deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation.
    Thromboxane B2-d<sub>9</sub>
  • HY-142165S
    (R)-Norverapamil-d6 hydrochloride
    (R)-Norverapamil-d6 (hydrochloride) is deuterium labeled (R)-Norverapamil.
    (R)-Norverapamil-</sub>d<sub>6</sub> hydrochloride
  • HY-W766807
    rac-1,2-Dilinoleoyl-3-chloropropanediol-d5
    rac-1,2-Dilinoleoyl-3-chloropropanediol-d5 (1,2-Dilinoleoyl-3-chloropropanediol-d5) is deuterium labeled rac-1,2-Dilinoleoyl-3-chloropropanediol.
    rac-1,2-Dilinoleoyl-3-chloropropanediol-d<sub>5</sub>
  • HY-B0083S1
    Leflunomide-13C6
    Leflunomide-13C6 (HWA486-13C6) is 13C labeled Leflunomide. Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.
    Leflunomide-<sup>13</sup>C<sub>6</sub>
  • HY-B1773AS1
    Sodium propionate-13C-1
    Sodium propionate-13C-1 is the 13C-labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease.
    Sodium propionate-<sup>13</sup>C-1
  • HY-66005S5
    Acetaminophen-d5
    Acetaminophen-d5 is deuterated-labeled Acetaminophen (HY-66005). Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-d<sub>5</sub>
  • HY-144386S
    N-Desmethyl L-ergothioneine methyl ester-d6
    N-Desmethyl L-ergothioneine methyl ester-d6 is the deuterium labeled N-Desmethyl L-ergothioneine methyl ester.
    N-Desmethyl L-ergothioneine methyl ester-d<sub>6</sub>
  • HY-W653916
    8-Hydroxy-2'-deoxyguanosine-13C,15N2
    8-Hydroxy-2'-deoxyguanosine-13C,15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
    8-Hydroxy-2'-deoxyguanosine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-132319S
    (-)-Corey lactone diol-heptyldioxolane-d15
    (-)-Corey lactone diol-heptyldioxolane-d15 is the deuterium labeled (-)-Corey lactone diol-heptyldioxolane.
    (-)-Corey lactone diol-heptyldioxolane-d<sub>15</sub>
  • HY-B1395S
    Mecamylamine-d3 hydrochloride
    Mecamylamine-d3 hydrochloride is the deuterium labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier.
    Mecamylamine-d<sub>3</sub> hydrochloride
  • HY-B1490AS
    Imipramine-d6
    Imipramine-d6 is the deuterium labeled Imipramine hydrochloride. Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects.
    Imipramine-d<sub>6</sub>
  • HY-150679S
    Remdesivir-13C6
    Remdesivir-13C6 is the 13C labeled Remdesivir.
    Remdesivir-<sup>13</sup>C<sub>6</sub>
  • HY-116776S
    Hexadecatetraenoic acid-d5
    Hexadecatetraenoic acid-d5 is deuterium labeled Hexadecatetraenoic acid. Hexadecatetraenoic acid is an unsaturated fatty acid that can be isolated from sardine oil.
    Hexadecatetraenoic acid-d<sub>5</sub>
  • HY-Y1169S2
    Fmoc-Asp(OtBu)-OH-d3
    Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis.
    Fmoc-Asp(OtBu)-OH-d<sub>3</sub>