Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1265)
Related Products (1265)
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DSPE-PEG1000-R9
0 ImagesCat. No.: HY-172277DSPE-PEG1000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG1000-R9 can be used for drug delivery.
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DSG-PEG5000-Mal
0 ImagesCat. No.: HY-183126CDSG-PEG5000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Undecyl 6-bromohexanoate
0 ImagesCat. No.: HY-W440810CAS No.: 959040-06-3Undecyl 6-bromohexanoate can be useful for the preparation of lipid nanoparticles.
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EDMPC
0 ImagesCat. No.: HY-143688CAS No.: 183283-19-4EDMPC, a cationic lipid, has an enhanced ability to deliver DNA to pulmonary tissues. EDMPC mediates intralobar DNA delivery to rodents.
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Gal-C4-Chol
0 ImagesCat. No.: HY-112752CAS No.: 219850-70-1Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles.
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DSPE-PEG3400-cRGD
0 ImagesCat. No.: HY-172464ADSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery.
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DSPE-PEG8 DBCO
0 ImagesCat. No.: HY-N16294CAS No.: 3091879-24-9DSPE-PEG8-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DSPE-PEG8-DBCO can be used to prepare lipid nanoparticles for drug delivery.
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DSPE-PEG2000-LTLRWVGLMS
0 ImagesCat. No.: HY-172485DSPE-PEG2000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG2000-LTLRWVGLMS can be used for drug delivery.
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E12CA1A3
0 ImagesCat. No.: HY-159870CAS No.: 2778182-26-4E12CA1A3 is a lipid transfection reagent that boosts the delivery efficiency of mRNA.
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DMG-PEG5000-Alkyne
0 ImagesCat. No.: HY-183191CDMG-PEG5000-Alkyne is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal alkyne group. DMG-PEG5000-Alkyne combines the membrane compatibility of phospholipids with the high reactivity of the alkyne group in click chemistry, making it suitable for research in biomaterial construction and drug delivery.
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16:0 TAP
0 Images16:0 TAP is a lipid product. 16:0 TAP can be used for the preparation of giant unilamellar vesicles to deliver agents.
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DPPE-PEG5000-NHS
0 ImagesCat. No.: HY-182833CCAS No.: 355150-30-0DPPE-PEG5000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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DSPE-PEG2000-SP94
0 ImagesCat. No.: HY-172500DSPE-PEG2000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG2000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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POPG-d62
0 ImagesCat. No.: HY-178787SSynonyms: PG(16:0/18:1)-d62; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)-d62POPG-d62 (PG(16:0/18:1)-d62) is the deuterium labeled POPG (HY-142991). POPG sodium salt is a negatively charged phospholipid. POPG sodium salt affects the interactions of membrane proteins with other molecules by changing the charge characteristics of the lipid environment. POPG sodium salt increases the apparent affinity of Gαq and Gβ1γ1 for activated NTS1. POPG sodium salt can interact with the positive charge of peptides. POPG sodium salt can be used in Parkinson's disease research.
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DMPE-PEG3000 ammonium
0 ImagesCat. No.: HY-155928CAS No.: 474922-82-2Synonyms: 14:0 PEG3000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammoniumDMPE-PEG3000 ammonium (14:0 PEG3000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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Stearic acid-PEG1000-NHS
0 ImagesCat. No.: HY-W440926Stearic acid-PEG1000-NHS is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond.
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DSPE-PEG1000-T7
0 ImagesCat. No.: HY-172722DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery.
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DSPE-PEG10000-Maleimide ammonium
0 ImagesCat. No.: HY-W441009DDSPE-PEG10000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG10000-Maleimide ammonium can be used in drug delivery research.
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Stearic acid-PEG2000-amine
0 ImagesCat. No.: HY-W440945Stearic acid-PEG2000-amine is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.
