2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Microphthalmia Associated Transcription Factor (MITF)
  5. Microphthalmia Associated Transcription Factor (MITF) Degrader

Microphthalmia Associated Transcription Factor (MITF) Degrader

Microphthalmia Associated Transcription Factor (MITF) Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-179717
    WZS0347
    		Degrader 99.06%
    WZS0347 is a MITF PROTAC degrader. WZS0347 effectively reduces the MITF protein levels in several melanoma cell lines, including B16F10, A375, and GAK. WZS0347 significantly inhibits the proliferation, migration, and invasion of melanoma cells. WZS0347 can be used for research on melanoma (Pink: MITF ligand: (HY-179718); Blue: CRBN ligand: (HY-131717); Black: linker: (HY-22391)).
  • HY-179718
    TT-012-Br
    		Degrader
    TT-012-Br (Compound 4) is a ligand for MITF and can be used for the synthesis of PROTACs, such as WZS0347 (HY-179717).