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Cat. No.: HY-106720A

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Amosulalol hydrochloride

(Synonyms: YM 09538 hydrochloride)

Amosulalol (YM 09538) hydrochloride is an orally active and dual inhibitor of α1/β1-Adrenergic Receptor. Amosulalol hydrochloride exhibits antihypertensive activity via α1-Adrenergic Receptor inhibition. Amosulalol hydrochloride decreases reflexogenic increases in heart rate and plasma renin activity (PRA) via β1-Adrenergic Receptor inhibition in spontaneously hypertensive rats (SHR).

For research use only. We do not sell to patients.

CAS No.: 70958-86-0
Formula: C₁₈H₂₅ClN₂O₅S
Molecular Weight:416.92

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Amosulalol hydrochloride Chemical Structure

CAS No.: 70958-86-0

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Fluorescent Dye

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Biological Activity

Description

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 70958-86-0
Molecular Weight 416.92
Formula C₁₈H₂₅ClN₂O₅S
SMILES

O=S(C1=CC(C(O)CNCCOC2=CC=CC=C2OC)=CC=C1C)(N)=O.Cl
Synonyms

YM 09538 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Honda K, et al. Autonomic and antihypertensive activity of oral amosulalol (YM-09538), a combined alpha- and beta-adrenoceptor blocking agent in conscious rats. Jpn J Pharmacol. 1985 May;38(1):31-41. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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Amosulalol hydrochloride

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Amosulalol hydrochloride Related Classifications

HY-106720A Related Classifications