2. Immunology/Inflammation
  3. MHC
  4. Anti-Mouse Vβ4 TCR Antibody (KT4)

Anti-Mouse Vβ4 TCR Antibody (KT4) is an anti-mouse Vβ4 TCR IgG2b monoclonal antibody. Anti-Mouse Vβ4 TCR Antibody (KT4) can reduce the proportion of Vβ4+ T cells without affecting their function. Anti-Mouse Vβ4 TCR Antibody (KT4) can be used for research on immunology and infection conditions such as virus infection. Anti-Mouse Vβ4 TCR Antibody (KT4) is often used in flow cytometry.

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Anti-Mouse Vβ4 TCR Antibody (KT4)

Anti-Mouse Vβ4 TCR Antibody (KT4) Estructura química

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Anti-Mouse Vβ4 TCR Antibody (KT4) Related Antibodies

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Descripciòn

Anti-Mouse Vβ4 TCR Antibody (KT4) is an anti-mouse Vβ4 TCR IgG2b monoclonal antibody. Anti-Mouse Vβ4 TCR Antibody (KT4) can reduce the proportion of Vβ4+ T cells without affecting their function. Anti-Mouse Vβ4 TCR Antibody (KT4) can be used for research on immunology and infection conditions such as virus infection. Anti-Mouse Vβ4 TCR Antibody (KT4) is often used in flow cytometry[1][2][3].

Isotype

Rat IgG2b
Recommend Isotype Controls
Species Reactivity

Mouse
In Vivo

Anti-Mouse Vβ4 TCR Antibody (KT4) (200 μg, i.p., on day 4 and day 2 before infection, on the day of infection, and once a week after infection) does not significantly prolong the survival time of transplanted skin in MHV68 virus injected C57BL/6 mice with a skin transplantation model[1].
Anti-Mouse Vβ4 TCR Antibody (KT4) (300 μg, i.p., once every 3 days, for 10 days) reduces the proportion of Vβ4+ T cells but does not affect their function in C57BL/6 mice with a MHV68 virus injection model[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 1×105 PFU MHV68 virus injected C57BL/6 mice (6-12 weeks)[1]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), on day 4 and day 2 before infection, on the day of infection, and once a week after infection
Result: Caused depletion of Vβ4+ T cells but failed to improve transplant rejection.
Animal Model: 1×103 PFU MHV68 virus injected C57BL/6 mice (8-14 weeks)[2]
Dosage: 300 μg
Administration: Intraperitoneal injection (i.p.), once every 3 days, for 10 days
Result: Reduced the proportion of Vβ4+ T cells.
Did not affect the production of IFNγ.
Application

in vivo administration; Flow cytometry
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

150 kDa

SMILES

[Anti-Mouse Vβ4 TCR Antibody (KT4)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Anti-Mouse Vβ4 TCR Antibody (KT4) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse Vβ4 TCR Antibody (KT4)MHCMajor Histocompatibility ComplexVβ4 TCRT cellsMHV68flow cytometryInhibitorinhibitorinhibit

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Nombre del producto:
Anti-Mouse Vβ4 TCR Antibody (KT4)
Cat. No.:
HY-P990142
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