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CD137/4-1BB Antibody (YA1506)

(Synonyms: TNFRSF9; 4-1BB; CD137; CDw137; ILA)
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CD137/4-1BB Antibody (YA1506) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD137/4-1BB.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4,5 % - 8 % trehalose.

  • Conjugation:
    Non-conjugated
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:50-1:100 1:10000

Product Details

Description

CD137/4-1BB Antibody (YA1506) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD137/4-1BB.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 28 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 27.9 kDa
Species Reactivity Database

Entrez Gene: 3604 Human

SwissProt: Q07011 Human

Immunogen

Recombinant human 4-1BB protein

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3103867

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4,5 % - 8 % trehalose.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CD137/4-1BB receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable)

  • Subcellular Localization

    Cell membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:Expressed on the surface of activated T cells

  • Subunit

    Interacts with TRAF1, TRAF2 and TRAF3 (PubMed:9418902, PubMed:9607925). Interacts with LRR-repeat protein 1/LRR-1 (PubMed:11804328)

  • SwissProt ID

    Q07011

  • Gene ID
    3604 [NCBI]
  • Synonyms

    TNFRSF9; 4-1BB; CD137; CDw137; ILA

  • Research Field

    Immunology

CD137/4-1BB Antibody (YA1506) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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    1/16
  • CD137/4-1BB Antibody (YA1506) Product Image