APC2 Antibody (YA3578)(PBS only)

Cat. No.: HY-P83881A: Data Sheet User Guide for Antibodies
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APC2 Antibody (YA3578) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to APC2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

APC2 Antibody (YA3578) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to APC2.

Host

Mouse

Molecular Weight

Predicted band size: 244 kDa;

Observed band size: 97 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O95996

Gene ID

10297 [NCBI]

Immunogen

Purified recombinant fragment of human APC2 (AA: 2041-2181) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases (PubMed:25753423). May also function in Wnt signaling by promoting the rapid degradation of CTNNB1 (PubMed:10021369, PubMed:11691822, PubMed:9823329)

Subcellular Localization：Cytoplasm, cytoskeleton; Golgi apparatus; Cytoplasm; Cytoplasm, perinuclear region

Expression：
Tissue_specificity:Widely expressed (at protein level) . Specifically expressed in the CNS

Isoforms & Post-Translational Modification：O95996 has 3 isomers: O95996-1: 243949 Da (predicted); O95996-2: 213799 Da (predicted); O95996-3: 243821 Da (predicted).

Subunit：Interacts with APC (PubMed:11691822). Interacts with CTNNB1 (PubMed:9823329). Interacts with MAPRE1 and MAPRE3 (PubMed:10644998). Interacts with TP53BP (PubMed:10646860). Interacts possibly with AXIN2 (PubMed:10021369)

Synonyms

APCL

Documentation

User Guide for Antibodies (1077 KB)